Adriana and Mia were spending a nice day at the pool when Sito comes in and starts insulting Adriana.  Getting ticked off she chases him into the kitchen.  Sito trips and crashes into Casey, followed by Ana crashing into Sito.  Casey drops her experiment, which explodes all over the two of them.  When Ana and Sito open their eyes, they find out that they’ve switched bodies.  To ensue more chaos and fighting, Ana, in Sito’s body, runs up to Philip’s room where Ariadne is confessing to having stolen Casey's crystal in order to scan herself.  “Sito” tells Ariadne that he’s still madly in love with her, which thoroughly angers Philip, who then punches “Sito”.

After calming down and changing clothes, they go their separate ways in the House.  Casey starts searching for her missing crystal while at the same time looking for a solution.  “Ana” locks “herself” in her room while “Sito” goes to hit on Tranns.  After a while, “Sito” confesses to Tranns that he’s Ana.  “Sito” then starts hitting on Valero, kissing him in front of Jesse, Jonas, Shawn, and Casey.  This brings Orix, Valero’s perverted side, out.  Valero then goes up to talk to “Ana”, asking “her” a million questions about Ana’s body.  When “Ana” goes to Sito’s room to get his sketchbook, Valero comes up from behind and gropes “her” breasts.  “Ana” fends him off and locks “herself” in her room again, upset.

Valero gives a present to Amorette and confesses his feelings for her.  He asks her to be his girlfriend, which she accepts.  At the same time, Jake tells Jesse not to get too cozy with Sic, which upsets Jesse, since he’s been getting feelings for her.  Jesse finally confesses to Sic, with much help and encouragement from Valero and Amorette, and asks Sic to be his girlfriend.  She accepts, which upsets Jake.  Sic talks with Jake and eventually cheers him up.

“Ana” talks to “Sito”, apologizing to “him” for the way “she’s” acted.  The two kiss, trying to see if they can switch bodies that way, but it doesn’t work.  “Sito” then says that Casey may have found a way to switch them.  Casey puts chemicals on each of their hands and has them hold hands.  Casey then chants something in Risan, and the two are back to normal.  Jonas, Shawn, Krysta, Jake, and Casey begin to celebrate in the bar.  Casey leaves suddenly, finding her crystal returned to her with traces of Andorian genetic matieral on it.